Testosterone Predicts Cognitive-Motor Brain Performance in Men and Women
A neuroimaging study from York University adds compelling evidence that testosterone supports brain function well beyond reproductive health — specifically in the neural networks that integrate thought and movement. Among 36 healthy working-age adults (18 female), researchers measured salivary hormone levels and used MRI imaging alongside touchscreen-based visuomotor tasks, including a cognitively demanding “cognitive-motor integration” […]
HRT as a Geroprotective Longevity Intervention
A paradigm-shifting perspective published in Aging and Disease reframes hormone replacement therapy from symptomatic relief to a fundamental geroprotective intervention capable of influencing biological aging mechanisms in women. The comprehensive review by Rabinovici et al. proposes that HRT mechanistically addresses all 12 hallmarks of aging and emphasizes that ovarian endocrine decline represents one of the […]
HRT Safety in BRCA Mutation Carriers
A groundbreaking study presented at the December 2025 San Antonio Breast Cancer Symposium challenges longstanding concerns about menopausal hormone therapy (MHT) in women with BRCA mutations. The matched prospective analysis of 1,352 menopausal women (676 matched pairs) with BRCA1 or BRCA2 mutations found that MHT use was inversely associated with breast cancer risk over a […]
Starting Hormone Therapy Sooner May Save Lives, Study Finds
Testosterone & Obesity Pharmacotherapy
New pooled data presented at ENDO 2025 (July 14, 2025) show that GLP-1 receptor agonists increased total testosterone levels in men with obesity compared to controls. This supports the connection between metabolic health and androgen status, suggesting that weight-loss pharmacotherapy may help restore endogenous testosterone. (ENDO 2025, Press Release) DHEA and Sex Hormones in […]
Skin Rejuvenation in Menopausal Women Using Hormone Therapy
A recent systematic review and meta-analysis published in the Journal of Menopausal Medicine explored the effects of Menopausal Hormone Therapy (MHT) on skin aging in women. The study aimed to evaluate whether MHT could positively influence skin elasticity, thickness, collagen content, and dryness in menopausal women aged 45–55 years. Key findings from the analysis, which […]
Breaking News: A Turning Point for Women’s Health and Hormone Therapy!
Is it time to revisit the recommendations for initiation of menopausal hormone therapy?
Progesterone’s Role in Sleep Quality
Study: Ogawa M, et al. Changes in Sleep Quality after Hormone Replacement Therapy with Micronized Progesterone in Japanese Menopausal Women. J Menopausal Med. 2025 Apr. PMCID: PMC12070122 Key Findings: A 2025 open-label study from Japan examined the effects of hormone replacement therapy (HRT) on sleep quality in peri- and postmenopausal women, focusing on the addition […]
Menopausal symptom burden as a predictor of mid- to late-life cognitive function and mild behavioral impairment symptoms
