A recent systematic review and meta-analysis published in the Journal of Menopausal Medicine explored the effects of Menopausal Hormone Therapy (MHT) on skin aging in women. The study aimed to evaluate whether MHT could positively influence skin elasticity, thickness, collagen content, and dryness in menopausal women aged 45–55 years.

Key findings from the analysis, which included 15 studies and 1,589 patients, revealed that MHT significantly improved skin elasticity and skin thickness. Additionally, the treatment increased collagen content in the skin, which is crucial for reducing wrinkles and maintaining skin structure. However, the effect on skin dryness was not found to be significant.

The study concludes that MHT can play a significant role in skin rejuvenation by enhancing elasticity and collagen content, contributing to a reduction in wrinkle severity and an increase in skin thickness. However, the authors emphasize the need for more rigorous clinical trials to further substantiate these findings.

Reference:

Pivazyan L, Avetisyan J, Loshkareva M, Abdurakhmanova A. Skin Rejuvenation in Women using Menopausal Hormone Therapy: A Systematic Review and Meta-Analysis. J Menopausal Med. 2023 Dec;29(3):97-111. doi: 10.6118/jmm.22042. PMCID: PMC10796198, PMID: 38230593.