A large real-world study using data from over 120 million women found that those who began estrogen therapy during perimenopause—rather than waiting until after menopause—had about 60% lower risks of breast cancer, heart attack, and stroke. This reinforces early hormone restoration supports long-term health, not just symptom relief. For BHRT providers, it underscores the importance of proactive, timely intervention—helping patients protect cardiovascular, neurologic, and breast health by addressing hormone decline before disease risk rises.
